Saturday, 30 August 2008

Pooling Of Birth Cohorts Provides Insights Into The Role Of Genes And The Environment In Asthma

�Atopy and asthma ar diseases that are known to be caused by
environmental factors and many genes. Since multiple genes and many environmental factors contribute to
disease evolution, one inevitably large groups of asthma patients and
unaffected controls in order to discover which genes and
environmental factors are important.


Dirkje S. Postma (University Medical Center Groningen, the
Netherlands) and his colleagues pooled data from three big Dutch
birth cohorts (PIAMA, PREVASC and KOALA).


This first prospective cohort study shows highly significant and
consistent associations at ages 1, 2, 4 and 8 age between allergic reaction
and the interleukin (IL)13 gene; IL13 is a protein critical in
allergy development.


Also, gene-environmental interactions were found in the pooled
analyses: polymorphisms in CD14 genes were associated with a lower
risk of exposure for atopic allergy at age 4 and 8 years in children who were exposed to
pets, with an opposite effect in non-exposed children.


The successful identification of gene - environment interactions when
pooling data from three well-characterised Dutch birth cohorts
justifies a confident attitude towards future studies that use pooled
data from age bracket studies.


These studies crataegus oxycantha improve insights into type I allergic reaction and bronchial asthma pathogenesis
and open novel avenues for preventive and therapeutic strategies.


Title Of The Original Article
Interleukin 13, CD14, favourite and tobacco smoke influence atopy in three Dutch cohorts: the allergenic study


The European Respiratory Journal is the peer-reviewed scientific publication of the European Respiratory Society (more than than 8,000 specialists in lung diseases and respiratory medicine in Europe, the
United States and Australia).

European Respiratory Journal

The European Respiratory Society (ERS)


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Wednesday, 20 August 2008

Urban review: Yo Majesty, Futuristically Speaking ... Never Be Afraid

Yo Majesty are Florida 's Shunda K and Jwl B , who differentiate in brutal booty-bass hip hop that replaces the usual stereotypes with a punky lesbian bent. Recently back from touring with CSS and the Gossip, the duet channel the outer edges of OutKast, with stripped, hyper- sexual electro-bass and they regular find space for a ballad.







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Sunday, 10 August 2008

Lily Allen Denies Breast Slip Was Deliberate

Lily Allen has responded to claims that she deliberately slipped a boob to gain publicity, saying that it simply wasn't the case.


The 'Smile' hitmaker - world Health Organization is presently finishing-off her second record album - reacted to the negative claims, by posting a message on her popular MySpace blog. Allen says:


"I wore a informal fitting jersey yesterday. I was selfsame hot in London yesterday and it's no secret I don't like eroding bras, in any case I don't need to, measuring in at 32A it scarcely seems necessary."


"My boob fell out twice and people on the blogs ar saying it was a publicity stunt." Lily continued. "Can I just say, I experience been keeping myself very much to myself recently, I've been gardening, decorating my newfangled flat and looking afterwards my bereaved grandfather."


"I'm actually trying really hard to be out of the public centre, as I'm really proud of the work I've put into my record album and I want multitude to value the music, yes I enjoy attention and praise, thats why I went into this job."


"But don't accuse me of purposely slipping out of my clothes to get attention and press. I hate the fact that there are always 10 middle aged men following me all over that I go."


Allen's second album is reportedly coroneted 'Stuck On The Naughty Step' and Lindsay Lohan is aforementioned to peach on 1 song named 'Wherever You Go'.




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